Frontiers in Marine Science ( IF 2.8 ) Pub Date : 2021-01-26 , DOI: 10.3389/fmars.2021.618779 Konrad Pomianowski , Artur Burzyński , Ewa Kulczykowska
The RNA sequencing data sets available for different fish species show a potentially high variety of forms of enzymes just in teleosts. This is primarily considered an effect of the first round of whole-genome duplication with mutations in duplicated genes (isozymes) and alternative splicing of mRNA (isoforms). However, the abundance of the mRNA transcript variants is not necessarily reflected in the abundance of active forms of proteins. We have investigated the transcriptional profiles of two enzymes, aralkylamine N-acetyltransferase (AANAT: EC 2.3.1.87) and N-acetylserotonin O-methyltransferase (ASMT: EC 2.1.1.4), in the eyeball, brain, intestines, spleen, heart, liver, head kidney, gonads, and skin of the European flounder (
中文翻译:
欧洲比目鱼(Platichthys flesus)的从头转录组大会:编码酶活性形式的转录本的预选。
可用于不同鱼类的RNA测序数据集显示出硬骨鱼类中存在多种潜在形式的酶。这主要被认为是第一轮全基因组复制对重复基因(同功酶)中的突变和mRNA的可变剪接(同工型)产生的影响。但是,mRNA转录变体的丰度并不一定反映在蛋白质活性形式的丰度中。我们研究了眼球,大脑,肠,脾脏,心脏,肝,头肾,性腺和欧洲比目鱼的皮肤(