The rise of multidrug-resistant human pathogenic bacteria is calling for alternative approaches to design antibacterial drugs. Here, we review new approaches based on antisense oligonucleotides as antibacterial agents, fecal microbiota transplantation, and antimicrobial peptides and cell-penetrating peptides with antibacterial activity.

中文翻译：

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针对耐药菌的新药物发现策略

具有多重耐药性的人类致病细菌的兴起要求设计抗菌药物的替代方法。在这里，我们综述了基于反义寡核苷酸作为抗菌剂，粪便微生物群移植以及具有抗菌活性的抗菌肽和细胞穿透肽的新方法。