Background

In recent years, studies have shown that cyfluthrin is harmful to the reproductive system. Lycium barbarum polysaccharide may be a protective agent.

Objective

To investigate the effect of cyfluthrin (Cy) on testosterone B (inhibin B, INHB) in male rats and the intervention of Lycium barbarum polysaccharide (LBP).

Results

Compared with the control group, the mRNA and protein expression levels of INH α and INH βB in the testis tissue decreased, and the difference was statistically significant (P < 0.05). The LBP intervention group can significantly increase the expression level, and the difference is statistically significant (P < 0.05).

Conclusion

The decrease of INHα and INHβB expression caused by Cy exposure indicates that Cy has a toxic effect on the testis of rats, and the addition of LBP has a certain protective effect on the testis of rats.

中文翻译：

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氟氰菊酯对大鼠睾丸抑制素B的影响及枸杞多糖的干预

背景

近年来的研究表明，氟氯氰菊酯对生殖系统有害。枸杞多糖可以是保护剂。

目的

目的研究氯氟氰菊酯（Cy）对雄性大鼠睾丸激素B（抑制素B，INHB）的影响以及枸杞多糖（LBP）的干预作用。

结果

与对照组相比，睾丸组织中INHα和INHβB的mRNA和蛋白表达水平下降，差异有统计学意义（P  <0.05）。LBP干预组可显着提高表达水平，差异具有统计学意义（P  <0.05）。

结论

Cy暴露引起的INHα和INHβB表达降低表明Cy对大鼠睾丸具有毒性作用，LBP的添加对大鼠睾丸具有一定的保护作用。