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Construction and Characterization of 3,7-Dichloro- N -(2,6-Diethylphenyl)- N -(2-Propoxyethyl)Quinolone-8-Carboxamide: A Potential Novel Pesticide Compound
Chemistry of Heterocyclic Compounds ( IF 1.4 ) Pub Date : 2021-02-03 , DOI: 10.1007/s10593-021-02866-x
Xi-Le Deng , Chun-Hui Zhu , Xiao-Mao Zhou , Lian-Yang Bai

A novel compound, 3,7-dichloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)quinoline-8-carboxamide was synthesized by splicing together a chloro-substituted quinoline moiety found in quinclorac (a selective herbicide) and a substituted amide moiety found in pretilachlor (another selective herbicide) using the active substructure splicing method. The chemical structure of this compound was characterized by 1H, 13C NMR, FTIR, high-resolution mass spectra and X-ray diffraction analysis. Pesticide potency (herbicidal and fungicidal activity) of this compound was evaluated. This compound displayed excellent control efficiency against Echinochloa crusgalli and also showed good fungicidal in vitro activity against Phytophthora capsici, Phytophthora sojae, and Phytophthora infestans.



中文翻译:

3,7-二氯-N-(2,6-二乙基苯基)-N-(2-丙氧基乙基)喹诺酮-8-羧酰胺的构建与表征:一种潜在的新型农药化合物

新型化合物3,7-二氯-N-(2,6-二乙基苯基)-N-(2-丙氧基乙基)喹啉-8-羧酰胺是通过将喹氯拉克(一种选择性除草剂)中发现的氯取代喹啉部分拼接在一起而合成)和丙草胺(另一种选择性除草剂)中发现的取代酰胺部分,采用活性亚结构剪接方法。该化合物的化学结构通过1 H,13 C NMR,FTIR,高分辨率质谱和X射线衍射分析进行表征。评估了该化合物的农药效力(除草和杀真菌活性)。该化合物显示出对十字花E的优异防治效果,并且在体外也显示出良好的杀真菌作用针对活动辣椒疫霉大豆疫霉菌,和晚疫病

更新日期:2021-02-03
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