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Construction and Characterization of 3,7-Dichloro-N-(2,6-Diethylphenyl)-N-(2-Propoxyethyl)Quinolone-8-Carboxamide: A Potential Novel Pesticide Compound

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Chemistry of Heterocyclic Compounds Aims and scope

A novel compound, 3,7-dichloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)quinoline-8-carboxamide was synthesized by splicing together a chloro-substituted quinoline moiety found in quinclorac (a selective herbicide) and a substituted amide moiety found in pretilachlor (another selective herbicide) using the active substructure splicing method. The chemical structure of this compound was characterized by 1H, 13C NMR, FTIR, high-resolution mass spectra and X-ray diffraction analysis. Pesticide potency (herbicidal and fungicidal activity) of this compound was evaluated. This compound displayed excellent control efficiency against Echinochloa crusgalli and also showed good fungicidal in vitro activity against Phytophthora capsici, Phytophthora sojae, and Phytophthora infestans.

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Authors and Affiliations

  1. Hunan Provincial Key Laboratory for Biology and Control of Weeds, Hunan Agricultural Biotechnology Research Institute, Hunan Academy of Agricultural Sciences, 2 Yuanda Road, Changsha, 410125, China

    Xi-Le Deng, Xiao-Mao Zhou & Lian-Yang Bai

  2. Institute of Plant Protection, Hunan Academy of Agricultural Science, 2 Yuanda Road, Changsha, 410125, China

    Chun-Hui Zhu

Authors
  1. Xi-Le Deng
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  2. Chun-Hui Zhu
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  3. Xiao-Mao Zhou
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  4. Lian-Yang Bai
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Correspondence to Lian-Yang Bai.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2021, 57(1), 49–54

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Deng, XL., Zhu, CH., Zhou, XM. et al. Construction and Characterization of 3,7-Dichloro-N-(2,6-Diethylphenyl)-N-(2-Propoxyethyl)Quinolone-8-Carboxamide: A Potential Novel Pesticide Compound. Chem Heterocycl Comp 57, 49–54 (2021). https://doi.org/10.1007/s10593-021-02866-x

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  • DOI: https://doi.org/10.1007/s10593-021-02866-x

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