Journal of Fluorescence ( IF 2.6 ) Pub Date : 2021-01-21 , DOI: 10.1007/s10895-020-02675-z Shiqing Zhang 1 , Xinyue Mu 1 , Liqiang Yan 1
Hypochlorite (ClO−) mediated by oxidative stress play an important role in the body's defense system due to their physiological and pathological significance. In this work, a new and simple probe was designed and synthesized to detect hypochlorite. This probe could rapidly respond to hypochlorite in a short time (20 s) in aqueous media, and showed excellent selectivity and sensitivity, and a wide pH range of 3 ̶ 12, as well as the low detection limit of 1.44 nM. In addition, it was successfully applied to the detection of ClO− in water sample, test paper experiment, and cell imaging.
Graphical Abstract
中文翻译:
用于快速检测次氯酸盐的荧光探针及其在水、试纸和活细胞中的应用
由氧化应激介导的次氯酸盐 (ClO - ) 由于其生理和病理意义而在人体防御系统中发挥重要作用。在这项工作中,设计并合成了一种新的简单探针来检测次氯酸盐。该探针可以在水介质中在短时间内(20 s)快速响应次氯酸盐,并表现出优异的选择性和灵敏度,以及 3 ̶ 12 的宽 pH 范围,以及 1.44 nM 的低检测限。此外,它被成功地应用于检测CLO的-水样品,试纸试验,和细胞成像英寸