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A Fluorescent Probe for the Fast Detection of Hypochlorite and its Applications in Water, Test Strip and Living Cells

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Abstract

Hypochlorite (ClO−) mediated by oxidative stress play an important role in the body's defense system due to their physiological and pathological significance. In this work, a new and simple probe was designed and synthesized to detect hypochlorite. This probe could rapidly respond to hypochlorite in a short time (20 s) in aqueous media, and showed excellent selectivity and sensitivity, and a wide pH range of 3 ̶ 12, as well as the low detection limit of 1.44 nM. In addition, it was successfully applied to the detection of ClO− in water sample, test paper experiment, and cell imaging.

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The authors declare that the data supporting the findings of this study are available in the article and the supplementary materials.

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Funding

This work was supported by Natural Science Foundation of Guangxi Province (2018GXNSFBA281070).

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Authors and Affiliations

  1. College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, Guangxi, 541006, People’s Republic of China

    Shiqing Zhang, Xinyue Mu & Liqiang Yan

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  1. Shiqing Zhang
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  2. Xinyue Mu
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Shiqing Zhang, Xinyue Mu and Liqiang Yan. The first draft of the manuscript was written by Liqiang Yan and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Liqiang Yan.

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Zhang, S., Mu, X. & Yan, L. A Fluorescent Probe for the Fast Detection of Hypochlorite and its Applications in Water, Test Strip and Living Cells. J Fluoresc 31, 569–576 (2021). https://doi.org/10.1007/s10895-020-02675-z

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