We studied the effect of long-term light deprivation which began at different stages of ontogeny on the content of α-tocopherol in rats during the first 3 months of postnatal development. In the offspring postnatally exposed to constant darkness, the level of α-tocopherol in the liver, kidneys, heart, skeletal muscles, and lungs was significantly decreased at the early stages of postnatal ontogeny (2 weeks and 1 month). In rats kept under constant darkness after birth, the content of α-tocopherol in the lungs was also reduced at the age of 1 month. The modulating effect of light deprivation on the level of α-tocopherol can be associated both with the impact of disturbed circadian rhythms and with increased content of melatonin in the body.

中文翻译：

---

长期光照剥夺对个体发育过程中大鼠α-生育酚含量的影响

我们研究了在个体发育的不同阶段开始的长期光照剥夺对出生后前 3 个月大鼠α-生育酚含量的影响。在出生后持续处于黑暗环境中的后代中，在出生后个体发育的早期阶段（2 周和 1 个月），肝脏、肾脏、心脏、骨骼肌和肺中的 α-生育酚水平显着降低。在出生后一直处于黑暗中的大鼠中，肺中 α-生育酚的含量在 1 个月大时也减少了。光照剥夺对 α-生育酚水平的调节作用可能与昼夜节律紊乱的影响和体内褪黑激素含量的增加有关。