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Effect of Long-Term Light Deprivation on α-Tocopherol Content in Rats during Ontogeny

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We studied the effect of long-term light deprivation which began at different stages of ontogeny on the content of α-tocopherol in rats during the first 3 months of postnatal development. In the offspring postnatally exposed to constant darkness, the level of α-tocopherol in the liver, kidneys, heart, skeletal muscles, and lungs was significantly decreased at the early stages of postnatal ontogeny (2 weeks and 1 month). In rats kept under constant darkness after birth, the content of α-tocopherol in the lungs was also reduced at the age of 1 month. The modulating effect of light deprivation on the level of α-tocopherol can be associated both with the impact of disturbed circadian rhythms and with increased content of melatonin in the body.

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Authors and Affiliations

  1. Institute of Biology, Federal Research Centre Karelian Research Centre of the Russian Academy of Sciences, Petrozavodsk, Russia

    I. V. Baishnikova, T. N. Ilyina, E. A. Khizhkin & V. A. Ilyukha

  2. Petrozavodsk State University, Petrozavodsk, Russia

    E. A. Khizhkin & I. A. Vinogradova

Authors
  1. I. V. Baishnikova
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  2. T. N. Ilyina
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  3. E. A. Khizhkin
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  4. V. A. Ilyukha
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  5. I. A. Vinogradova
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Corresponding author

Correspondence to I. V. Baishnikova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 170, No. 9, pp. 281-295, September, 2020

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Baishnikova, I.V., Ilyina, T.N., Khizhkin, E.A. et al. Effect of Long-Term Light Deprivation on α-Tocopherol Content in Rats during Ontogeny. Bull Exp Biol Med 170, 294–298 (2021). https://doi.org/10.1007/s10517-021-05054-1

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  • DOI: https://doi.org/10.1007/s10517-021-05054-1

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