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Experimental Extracellular Matrix of the Xenoperitoneum: Comprehensive Assessment of a New Biological Material for Plastic Surgery of Anterior Abdominal Wall Defects
Bulletin of Experimental Biology and Medicine ( IF 0.9 ) Pub Date : 2021-01-01 , DOI: 10.1007/s10517-021-05068-9
L V Maxyatkina 1 , R M Badyrov 1 , N T Abatov 1 , L L Akhmaltdinova 1
Affiliation  

A new biological implant, extracellular matrix of bovine peritoneum, was developed and obtained for plastic surgery of the anterior abdominal wall defects. The material was implanted to rats into the anterior abdominal wall. The content of rejection markers (TNF, IL-2, C-reactive protein) and the morphological picture of the implantation zone at the early stages (30 days) after surgery were evaluated. The studied material at this stage demonstrated adequate biocompatibility; the formation of mature, consistent contact with the tissues of the anterior abdominal wall and minimum tissue inflammatory reactions were observed.

中文翻译:

Xenoperitoneum 的实验性细胞外基质:一种用于腹前壁缺损整形手术的新型生物材料的综合评估

开发并获得了一种新的生物植入物,牛腹膜细胞外基质,用于前腹壁缺损的整形手术。该材料被植入大鼠的前腹壁。评估排斥标志物(TNF、IL-2、C反应蛋白)的含量和术后早期(30天)植入区的形态学图片。在这个阶段研究的材料表现出足够的生物相容性;观察到与前腹壁组织形成成熟、一致的接触和最小的组织炎症反应。
更新日期:2021-01-01
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