Impacts of titanium dioxide nanoparticles (TiO₂ NPs) on serum glucose, albumin, total protein, cholesterol, triglyceride, sodium (Na⁺), potassium (K⁺), and chloride ion (Cl⁻) levels and serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and cholinesterase (ChE) activities of Clarias gariepinus were determined after exposing the fish to 1, 5 and 10 mg/L titanium applied as TiO₂ over 1, 4 and 7 days. No mortality was observed during the experiments. Serum glucose and albumin levels increased while serum total protein, cholesterol and triglyceride levels decreased compared to control at the end of the 7th day. Serum Na⁺, K⁺ and Cl⁻ levels of C. gariepinus decreased after 7 days of exposure to 10 mg/L TiO₂ NPs. ChE activity decreased and AST, ALT, ALP activities increased at all exposure concentrations and LDH activities increased compared to control after 4 and 7 days of exposure to TiO₂ NPs in C. gariepinus.

二氧化钛纳米颗粒的影响（的TiO _2个上的血清葡萄糖，白蛋白，总蛋白，胆固醇，甘油三酯，钠（Na NPS）⁺），钾（K ⁺），和氯离子（CL ^- ）水平和血清天冬氨酸转氨酶（AST）将鱼暴露于1、5和10 mg / L作为TiO _2的钛中后，测定了Clarias gariepinus的丙氨酸氨基转移酶（ALT），碱性磷酸酶（ALP），乳酸脱氢酶（LDH）和胆碱酯酶（ChE）活性。超过1、4和7天。实验期间未观察到死亡率。在第7天结束时，与对照组相比，血清葡萄糖和白蛋白水平升高，而血清总蛋白，胆固醇和甘油三酸酯水平降低。血清的Na ⁺，K ⁺和Cl ^-的水平C.鲇7天后暴露降低到10毫克/ L的TiO _2个纳米颗粒。与对照相比，暴露于C. gariepinus的TiO ₂ NP后4天和7天，ChE活性均降低，AST，ALT，ALP活性升高，LDH活性升高。