4-iodophenylboronic acid (IPBA) ligated luminescent gold cluster was synthesized by mixing an aqueous solution of IBPA and polyvinylpyrrolidone stabilized gold cluster (Au:PVP) in water at room temperature through chemisorption of iodine on gold nano surface. Transmission Electron microscopy (TEM) and matrix assisted laser desorption ionization (MALDI) analysis revealed that the size of these Au-clusters (1.4±0.2 nm) remain unchanged without any noticeable aggregation during synthesis. Owing to the formation of excimer between aryl moieties grafted over Au surface, the cluster exhibit strong emission peak at 335 nm. This luminescent gold cluster is used for sensing different saccharides in water at physiological pH through quenching of excimer emission peak. This strong excimer emission is significantly quenched in presence of saccharides through interaction with boronic acid moieties. The selectivity for different saccharides follows the order: fructose > galactose > maltose > glucose ~ ribose > sorbitol with hight affinity for fructose (K_SV = 1.54 × 10⁴ M⁻¹) with Limit of Detection (LOD) of 100 μM.

Graphical Abstract

中文翻译：

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基于准分子发射猝灭的4-碘苯基硼酸稳定的金簇作为糖类的新型荧光化学传感器

在室温下，通过碘在金纳米表面的化学吸附，将IBPA水溶液和聚乙烯吡咯烷酮稳定的金簇（Au：PV​​P）水溶液混合，合成了4-碘苯基硼酸（IPBA）连接的发光金簇。透射电子显微镜（TEM）和基质辅助激光解吸电离（MALDI）分析表明，这些Au团簇的尺寸（1.4±0.2 nm）保持不变，并且在合成过程中没有任何明显的聚集。由于在Au表面上接枝的芳基部分之间形成准分子，该簇在335nm处显示出强发射峰。该发光的金簇用于通过抑制受激准分子发射峰来在生理pH值下感测水中的不同糖类。通过与硼酸部分的相互作用，在糖类存在下，这种强烈的准分子发射被显着淬灭。对不同糖类的选择性遵循以下顺序：果糖>半乳糖>麦芽糖>葡萄糖〜核糖>对果糖具有高亲和力的山梨醇（K_SV = 1.54×10 ⁴  M ^-1），检测限（LOD）为100μM。

图形概要