Nowadays plant origin compounds with anti-cancer properties come into prominence, among them is curcumin (CUR) with a remarkable anti-cancer activity against various cancers. CUR was nanoformulated (CUR-PLGA) by the polymer based poly(lactic- co -glycolic acid) (PLGA) and both CUR and CUR-PLGA were radiolabeled with iodine-131 radionuclide for investigation of their in vitro behaviour on Human cervix adenocarcinoma (HeLa) and Ovarian endometrioid adenocarcinoma (MDAH-2774) cell lines. The newly described radiolabeled CUR and CUR-PLGA may be initiative discovery of novel potential imaging and therapeutic agents.

中文翻译：

---

使用 HeLa 和 MDAH-2774 细胞研究放射性标记姜黄素的纳米制剂和掺入潜力

如今，具有抗癌特性的植物源性化合物越来越突出，其中姜黄素（CUR）对各种癌症具有显着的抗癌活性。CUR 由基于聚合物的聚（乳酸 - 共 - 乙醇酸）（PLGA）制成纳米制剂（CUR-PLGA），CUR 和 CUR-PLGA 均用碘 131 放射性核素进行放射性标记，以研究它们对人宫颈腺癌的体外行为。 HeLa) 和卵巢子宫内膜样腺癌 (MDAH-2774) 细胞系。新描述的放射性标记 CUR 和 CUR-PLGA 可能是新型潜在成像和治疗剂的主动发现。