In this work, we report a novel nonenzymatic glucose detection base on the use of Au (111)-like/SiO₂ indium tin oxide (ITO) electrode. First, the ordered SiO₂-cavity array was fabricated on the ITO electrodes via the ordered polystyrene spheres (PS) templates. Secondly, the nucleation stage of Au NPs was generated by an electrochemical seeding growth method. As a matter of fact, \( AuCl_{4}^{ - } \) could be electrodeposited on the as-prepared Au seeds in a subsequent cyclic voltammetry, the raspberry-like Au NPs were formed with major facet of (111). The size and density of raspberry-like Au NPs could be successfully controlled. The as-prepared electrode showed good electrochemical performance for glucose oxidation with the linear range from 50 μM to 1.5 mM (R = 0.9995), a low detection limit of 12 μM, and good selectivity of the interferences of AA and UA. The raspberry-like Au (111)-like/SiO₂ ITO electrode might become an enzyme-free glucose sensor with long-term stability and good reproducibility.

在这项工作中，我们报告基于使用Au（111）样/ SiO ₂铟锡氧化物（ITO）电极的新型非酶法葡萄糖检测。首先，通过有序的聚苯乙烯球（PS）模板在ITO电极上制造了有序的SiO ₂腔阵列。其次，通过电化学晶种生长法产生了金纳米颗粒的成核阶段。实际上，\（AuCl_ {4} ^ {-} \）可以在随后的循环伏安法中将其电沉积在制备好的Au种子上，形成树莓状的Au NP，其主要小面为（111）。覆盆子状金纳米颗粒的大小和密度可以成功地控制。所制备的电极显示出良好的葡萄糖氧化电化学性能，线性范围为50μM至1.5 mM（R  = 0.9995），检测限低至12μM，并且对AA和UA的干扰具有良好的选择性。像树莓般的Au（111）样/ SiO ₂ ITO电极可能成为无酶的葡萄糖传感器，具有长期稳定性和良好的重现性。