Fungi have provided intriguing chemical diversity and have additionally proven to be a tremendous source for a great variety of therapeutic molecules. Various fungal glycosides have been reported from fungi and the majority of these metabolites possess cytotoxic and antimicrobial effects. Although natural products are obtained in most cases in small amounts from the specific natural source, total syntheses of these valuable commodities remain one of the most important ways of obtaining them on a large scale for more detailed and comprehensive biological studies. In addition, the total synthesis of secondary metabolites is a useful tool, not only for the disclosure of novel complex pharmacologically active molecules but also for the establishment of cutting-edge methodologies in synthetic chemistry. Numerous fungal glycosides have been synthesized in the last four decades regarding the following natural product classes viz., tetramic acid glycosides (epicoccamides A and D), polyketide glycosides (TMC-151C), 2-pyrone glycosides (epipyrone A), diterpene glycosides (sordarin), depside glycosides (CRM646-A and –B, KS-501 and KS- 502), caloporosides (caloporoside A), glycolipids (emmyguyacins A and B, acremomannolipin A), and cerebrosides (cerebroside B, Asperamide B, phalluside-1, Sch II). The current literature review about fungal glycoside synthetic studies is, therefore, of interest for a wide range of scientists and researchers in the field of organic, natural product, and medicinal chemists as it outlines key strategies of fungal glycosides and, in particular, glycosylation, the known biological and pharmacological effects of these natural compounds have afforded a new dimension of exposure.

真菌提供了令人着迷的化学多样性，并被证明是治疗分子种类繁多的巨大来源。真菌中已报道了各种真菌糖苷，这些代谢产物中的大多数具有细胞毒性和抗菌作用。尽管大多数情况下都是从特定的天然来源中少量获取天然产物，但是这些有价值的商品的总合成仍然是大规模获取更重要，更全面的生物学研究的最重要方法之一。此外，次级代谢产物的全合成是有用的工具，不仅用于公开新型复杂的药理活性分子，而且用于建立合成化学领域的前沿方法。在过去的四十年中，关于以下天然产物类别，合成了许多真菌糖苷，即四酸糖苷（二十碳酰胺A和D），聚酮糖苷（TMC-151C），2-吡喃酮苷（表吡喃酮A），二萜糖苷（蜜柑苷），深度糖苷（CRM646-A和-B，KS-501和KS-502），钙葡糖苷（钙葡糖苷A），糖脂（emmyguyacins A和B，acremomannolipin A）和脑苷脂（脑苷B，Asperamide B，phalluside- 1，Sch II）。因此，当前有关真菌糖苷合成研究的文献综述引起了有机，天然产物和药物化学领域的众多科学家和研究人员的兴趣，因为它概述了真菌糖苷的关键策略，尤其是糖基化，