This study describes the morphology of a filamentous non-heterocystous blue-green alga (cyanobacterium) Oscillatoria princeps isolated from the Bhabakundalswara sea mouth, its use in biogenic synthesis of silver nanoparticles (AgNPs), along with antimicrobial studies using multidrug resistant (MDR) methicillin-resistant strains of Staphylococcus aureus (MRSA), Streptococcus pyogenes and Escherichia coli, isolated from clinical samples. The synthesized O. princeps -AgNPs were characterized with UV–visible spectrometry, scanning electron microscopy (SEM), X-ray diffraction (XRD), dynamic light scattering analysis (DLS) and Fourier transform infrared spectroscopy (FT-IR) analyses. The synthesized AgNPs had remarkable antibacterial activities against MDR strains of MRSA, S. pyogenes and E. coli with the inhibitory zone sizes, 14–16 mm as recorded from agar well diffusion method, while MIC values were 100, 80, 60 µg/ml, for the respective cited bacterial species. Thus, O. princeps -AgNPs in future would be druggable antibacterials.

这项研究描述了从Bhabakundalswara海口分离出的丝状非杂种蓝绿藻（蓝藻）Oscillatoria princeps的形态，其在银纳米颗粒（AgNPs）的生物合成中的用途，以及使用耐多药（MDR）的甲氧西林进行的抗菌研究从临床样本中分离出的金黄色葡萄球菌（MRSA），化脓性链球菌和大肠杆菌的耐药菌株。合成Ø。王子通过紫外可见光谱，扫描电子显微镜（SEM），X射线衍射（XRD），动态光散射分析（DLS）和傅里叶变换红外光谱（FT-IR）分析对-AgNPs进行了表征。合成的AgNPs对MRSA，化脓性链球菌和大肠杆菌的MDR菌株具有显着的抗菌活性，如琼脂孔扩散法所记录的，抑菌圈大小为14-16 mm，而MIC值为100、80、60 µg / ml ，分别用于引用的细菌种类。因此，O。王子-AgNPs将来会成为可治疗的抗菌药物。