The pathogenesis of diseases of the gastrointestinal tract in horses is accompanied by inflammation and oxidative stress and may be caused by a lack of nitric oxide, which controls various signaling pathways in the body. The level of nitrites, which are metabolites of nitric oxide in horses with various intestinal diseases, has been evaluated in blood serum at 3.60 ± 3.02 μM and 8.3 ± 6.0 μM in horses at ages of 7–26 years and 1–5 years, respectively. A sharp reduction in the nitrite concentrations was observed in all horses with intestinal diseases (3.39 ± 2.85 μM), especially in horses with tympanitic caecum (0.6 ± 0.4 μM) and obstruction of the colon (0.81 ± 0.5 μM).

中文翻译：

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绞痛马的一氧化氮生物利用度降低：ESR 光谱评估

马胃肠道疾病的发病机制伴随着炎症和氧化应激，可能是由于缺乏控制体内各种信号通路的一氧化氮所致。亚硝酸盐是患有各种肠道疾病的马的一氧化氮代谢物，在 7-26 岁和 1-5 岁的马中，其血清中的亚硝酸盐水平分别为 3.60 ± 3.02 μM 和 8.3 ± 6.0 μM。 . 在所有患有肠道疾病的马中观察到亚硝酸盐浓度急剧下降 (3.39 ± 2.85 μM)，尤其是在有盲肠鼓膜 (0.6 ± 0.4 μM) 和结肠阻塞 (0.81 ± 0.5 μM) 的马中。