Self emulsifying drug delivery system (SEDDS), a category of lipid based technology has gained interest in the recent years for enhancement of solubility and bioavailability of poorly water soluble drugs. With the progress of research in this field, novel excipients have been developed with enhanced properties. But excipient selection is the key hurdle in the formulation of SEDDS. The objective of this review is to summarize different types of oils, surfactants, co-surfactants which are the key components of liquid SNEDDS, various carriers utilized in the conversion of liquid SNEDDS to solid SNEDDS, their description, properties, grades and applications in pharmacy. This article provides an overview of solidification techniques to transform L-SEDDS to S-SEDDS which are more stable and have better patience compliance. This review presents numerous literature reports on various excipients used and the discussion on how these excipients affect the final results.

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自我乳化给药系统新型赋形剂的见解及其意义：最新评论

近年来，自乳化药物递送系统（SEDDS）是一类基于脂质的技术，其目的是提高水溶性差的药物的溶解度和生物利用度。随着该领域研究的进展，已经开发了具有增强性能的新型赋形剂。但是，辅料的选择是制定SEDDS的关键障碍。这篇综述的目的是总结不同类型的油，表面活性剂，助表面活性剂（它们是液体SNEDDS的关键成分），用于将液体SNEDDS转化为固体SNEDDS的各种载体，它们的描述，性质，等级和在药学上的应用。本文概述了将L-SEDDS转换为S-SEDDS的固化技术，该技术更稳定且耐心性更好。