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Critical Reviews™ in Therapeutic Drug Carrier Systems

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ISSN Print: 0743-4863

ISSN Online: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

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Insights into Novel Excipients of Self-Emulsifying Drug Delivery Systems and Their Significance: An Updated Review

Volume 38, Issue 2, 2021, pp. 27-74
DOI: 10.1615/CritRevTherDrugCarrierSyst.2020034975
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ABSTRACT

Self-emulsifying drug delivery system (SEDDS), a category of lipid-based technology, has gained interest in the recent years for enhancement of solubility and bioavailability of poorly water-soluble drugs. With the progress of research in this field, novel excipients have been developed with enhanced properties. But excipient selection is the key hurdle in the formulation of SEDDS. The objective of this review is to summarize different types of oils, surfactants, co-surfactants which are the key components of liquid SEDDS (L-SEDDS), various carriers utilized in the conversion of L-SEDDS to solid SEDDS (S-SEDDS), their description, properties, grades, and applications in pharmacy. This article provides an overview of solidification techniques to transform L-SEDDS to S-SEDDS which are more stable and have better patience compliance. This review presents numerous literature reports on various excipients used and the discussion on how these excipients affect the final results.

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CITED BY
  1. Salawi Ahmad, Self-emulsifying drug delivery systems: a novel approach to deliver drugs, Drug Delivery, 29, 1, 2022. Crossref

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