The high enhancement factor (EF) of surface-enhanced Raman (SERS) probes is an important parameter for high-sensitivity Raman scattering measurement applied to environment control. In this article, we present a SERS probe based on silver nano-structures deposited on silica microsphere surfaces made by the laser-assisted photochemical method and reflection converging mirror for a high EF Raman measurement of ultralow organic compound concentration inliquid environments. The laser-assisted photochemical method can synthesize and homogeneously deposit nano-silvers on a silica microsphere, and the reflection converging mirror can collect more Raman signal to the photo-detector and give high Raman enhancement of the SERS probe. The SERS-activity of the probe is verified by the detection of ultralow concentrations of Rhodamine 6 G in aqueous solutions in the range of 10⁻⁴–10⁻¹⁰ M. The obtained results show that the proposed SERS probe has an increase of collected Raman intensity up to 32% in comparison to a SERS probe without reflection converging mirror, and an EF of the SERS probe achieved up to 1.8 10¹⁰. We believe that the novel SERS probe has a large potential for applications in biochemical sensing techniques.

表面增强拉曼（SERS）探针的高增强因子（EF）是应用于环境控制的高灵敏度拉曼散射测量的重要参数。在本文中，我们介绍了一种基于银纳米结构的SERS探针，该银纳米结构沉积在通过激光辅助光化学方法和反射会聚镜制成的二氧化硅微球表面上，用于在液体环境中进行超低有机化合物浓度的高EF拉曼测量。激光辅助光化学方法可以合成纳米银并将其均匀地沉积在二氧化硅微球上，并且反射会聚镜可以将更多的拉曼信号收集到光探测器，并提高SERS探针的拉曼增强。⁻⁴ –10 ^-10M。获得的结果表明，与没有反射会聚镜的SERS探针相比，所建议的SERS探针的拉曼强度提高了32％，SERS探针的EF达到了1.8 10 ¹⁰。我们相信，新型SERS探针在生化传感技术中具有广阔的应用前景。