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Gold/Lewis acid catalyzed oxidative cyclization involving activation of nitriles
Chemical Communications ( IF 4.3 ) Pub Date : 2020-11-17 , DOI: 10.1039/d0cc06875f
Ali Wang 1, 2, 3, 4, 5 , Xin Xie 1, 2, 3, 4, 5 , Chunli Zhang 1, 2, 3, 4, 5 , Yuanhong Liu 1, 2, 3, 4, 5
Affiliation  

A gold-catalyzed oxidative cyclization of alkyne–nitriles using water or alcohol as the external nucleophiles has been developed. The catalytic system, featured with gold and Lewis acid dual catalysis, allows a facile synthesis of functionalized isoquinolin-1(2H)-ones and 1-alkoxy-isoquinolines with a wide structural diversity.

中文翻译:

金/路易斯酸催化的氧化环化涉及腈的活化

已经开发了一种以水或酒精为外部亲核试剂的金催化炔腈的氧化环化反应。该催化体系具有金和路易斯酸双重催化功能,可轻松合成功能多样的功能化异喹啉-1(2 H)-ones和1-烷氧基异喹啉。
更新日期:2020-11-27
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