An effective hemostatic composite material was obtained due to the combination of water-absorption, protein-sorption, and hemostatic properties of highly dispersed oxides of SiO2 and Al2O3 with the cellular structure of polyurethane foam. It was found that a sample with a silica content of 5 wt.% has the highest parameters of osmotic activity and water absorption. The protein-adsorption activity of the fillers in the composite is slightly reduced, but remains at a level sufficient for the manifestation of biological activity. The hemostatic effect of the composite materials was studied in a model of parenchymal bleeding in rats.

中文翻译：

---

硅和氧化铝填充聚氨酯泡沫复合材料的蛋白质吸附和止血性能

由于高度分散的SiO2和Al2O3氧化物的吸水、蛋白质吸附和止血性能与聚氨酯泡沫的多孔结构相结合，获得了一种有效的止血复合材料。发现二氧化硅含量为 5 wt.% 的样品具有最高的渗透活性和吸水参数。复合材料中填料的蛋白质吸附活性略有降低，但仍保持在足以表现生物活性的水平。在大鼠实质出血模型中研究了复合材料的止血作用。