More and more attention has been paid to the structurally diverse indazole analogs in recent years which are widely present in numerous commercially available drugs. Indazole-containing derivatives are endowed with a broad range of biological properties, such as anti-inflammatory, antibacterial, anti-HIV, antiarrhythmics, antifungal and antitumor activities. This review is a guide for pharmacologists who are in search of valid preclinical/clinical drug compounds where the progress, from 1966 to the present day, of approved marketed drugs containing indazole scaffold is examined.

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吲唑支架：市售和临床药物的通才

近年来，结构多样化的吲唑类似物受到越来越多的关注，它们广泛存在于许多市售药物中。含吲唑的衍生物具有广泛的生物学特性，例如抗炎，抗菌，抗HIV，抗心律不齐，抗真菌和抗肿瘤活性。这篇综述为正在寻找有效的临床前/临床药物化合物的药理学家提供指南，该研究对1966年至今的批准的含吲唑支架的上市药物的进展进行了研究。