Myelotoxicity is a serious side effect of anticancer drugs. The search for drugs that can reduce the hematological complications of chemotherapy through modulation of hematopoietic stem cells is an urgent task of oncopharmacology. In the present study we showed that administration of Tussilago farfara L. polysaccharides to C57BL/6 mice treated with cyclophosphamide can increase the number of hematopoietic stem cells (CD117 + 34 + ) in the bone marrow.

中文翻译：

---

Tussilago farfara L.多糖对环磷酰胺处理小鼠骨髓造血干细胞(CD117+34+)含量的影响

骨髓毒性是抗癌药物的严重副作用。寻找可以通过调节造血干细胞来减少化疗血液学并发症的药物是肿瘤药理学的一项紧迫任务。在本研究中，我们表明向用环磷酰胺治疗的 C57BL/6 小鼠施用 Tussilago farfara L. 多糖可以增加骨髓中造血干细胞 (CD117 + 34 + ) 的数量。