Abstract

The principal objective of this study is to evaluate the protective effect of cysteamine (Cym) against oxidation by chelating with metal cations. Cym–Zn complex has been prepared through a simple procedure using Cym ⋅ HCl and ZnSO₄. The results have shown that the chelating efficiency of zinc is better when the molar ratio of the reactant Cym · HCl to zinc ions is 1.4–1.5. IR spectra of as-synthesized Cym–Zn complex suggests Cym cross-links with Zn through N and S atoms. X-ray powder diffraction analysis shows that the crystal structure is consisted of a coordination unit [Zn₂(SC₂H₆N)₃], a chlorine atom and an H₂O molecule. Besides, the cell parameters of the monoclinic crystal are a = 7.9581(5) Å, b = 15.0794(10) Å, c = 12.2910(8) Å and β = 103°. Cym retention rate and thermal decomposition characteristics of Cym–Zn complex are significantly improved, and doping of iron, copper and manganese cations is helpful to suppress Cym oxidization because of the formation of stronger bonds with sulfur atom than zinc cation. The investigation indicates metal ion is an effective inhibitor for Cym oxidation.

中文翻译：

---

锌（II）-半胱胺配合物的合成，晶体结构和半胱胺稳定性的提高

摘要

这项研究的主要目的是通过与金属阳离子螯合来评估半胱胺（Cym）对氧化的保护作用。通过使用Cym⋅HCl和ZnSO ₄的简单程序制备了Cym-Zn复合物。结果表明，当反应物Cym·HCl与锌离子的摩尔比为1.4-1.5时，锌的螯合效率更好。合成后的Cym–Zn络合物的红外光谱表明，Cym通过N和S原子与Zn发生交联。X射线粉末衍射分析表明，晶体结构由配位单元[Zn ₂（SC ₂ H ₆ N）₃ ]，氯原子和H ₂ O分子组成。此外，单斜晶体的晶胞参数为a = 7.9581（5）Å，b = 15.0794（10）Å，c = 12.2910（8）Å和β= 103°。Cym-Zn络合物的Cym保留率和热分解特性得到显着改善，铁，铜和锰阳离子的掺杂有助于抑制Cym氧化，因为与硫原子形成的键比锌阳离子更牢固。研究表明金属离子是Cym氧化的有效抑制剂。