Drug delivery is the process of administering drugs at a specific amount in a specific site. Hydroxyapatite (HA) is reported as a drug carrier because of its unique properties such as high biodegradability, biocompatibility and drug-loading capacity, easy preparation, sterilization and cost-effective production. In the present study, the nanohydroxyapatite was synthesized at various calcination temperatures by the sol–gel route. The results revealed that the synthesized HA at 700 °C had the highest crystallinity. Moreover, the loading content of ampicillin was studied on HA samples synthesized at different calcination temperatures. It is considered that synthesized HA at 500 °C provided appropriate surface for ampicillin loading. The synthesized HA was characterized by scanning electron microscopy, X-ray diffraction, Fourier transform infrared and UV/Vis spectroscopy techniques before and after ampicillin loading.

药物输送是在特定位置以特定量给药的过程。据报道，羟基磷灰石（HA）由于其独特的特性如高生物降解性，生物相容性和载药量，易于制备，灭菌和具有成本效益的生产而成为药物载体。在本研究中，纳米羟基磷灰石是通过溶胶-凝胶途径在各种煅烧温度下合成的。结果表明，合成的HA在700℃下具有最高的结晶度。此外，还研究了在不同煅烧温度下合成的HA样品中氨苄西林的负载量。认为在500°C下合成的HA为氨苄西林负载提供了合适的表面。合成的HA通过扫描电子显微镜，X射线衍射，