This study aims to construct tissue engineering stents by using the long fiber-reinforced thermoplastic (LFT) technique to develop artery stents. The experimental method combines fibers, the LFT technique, and electrospinning technique. First, the biodegradable polyvinyl alcohol yarns are twisted and coated in polycaprolactone/polyethylene glycol blends through the LFT technique. Next, the weft-knitting and heat treatment are used to establish the stent structure, after which poly(ethylene oxide) (PEO) is electrospun to coat the stents. The morphology, mechanical, and biological properties of tissue engineering stents are evaluated. The test results indicated that the use of the LFT technique retains the softness of filaments, which facilitates the subsequent weft-knitting process. The coating of blends and electrospinning of PEO have a positive influence on the tissue engineering stents, as demonstrated by the tensile strength of 59.93 N and compressive strength of 6.10 N. Moreover, the in vitro degradation of stents exhibits a stabilized process. The water contact angle is 20.33°, and the cell survival rate in 24 h is over 80%. The proposed tissue engineering stents are good candidates for artery stent structure.

本研究旨在通过使用长纤维增强热塑性塑料 (LFT) 技术开发动脉支架来构建组织工程支架。实验方法结合了纤维、LFT 技术和静电纺丝技术。首先，通过 LFT 技术将可生物降解的聚乙烯醇纱线加捻并涂上聚己内酯/聚乙二醇混合物。接下来，使用纬编和热处理来建立支架结构，然后静电纺丝聚（环氧乙烷）（PEO）以涂覆支架。评估组织工程支架的形态、机械和生物学特性。测试结果表明，LFT技术的使用保留了长丝的柔软度，有利于后续的纬编工艺。PEO 的共混涂层和静电纺丝对组织工程支架具有积极影响，拉伸强度为 59.93 N，压缩强度为 6.10 N。此外，支架的体外降解表现出稳定的过​​程。水接触角为20.33°，24小时细胞存活率超过80%。所提出的组织工程支架是动脉支架结构的良好候选者。