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Synthetic approaches to pyrido[1,2- a ]indoles (microreview)
Chemistry of Heterocyclic Compounds ( IF 1.4 ) Pub Date : 2020-10-19 , DOI: 10.1007/s10593-020-02790-6
Igor L. Nikonov , Dmitry S. Kopchuk , Grigory V. Zyryanov , Oleg N. Chupakhin

The review presents the main methods for the synthesis of pyrido[1,2-a]indoles and their annulated and conjugated derivatives over the past 10 years. The approaches are divided into three groups depending on the starting compounds: construction of the pyridine nucleus on the indole fragment, cyclization using benzylsubstituted pyridines, and formally one-step process via aryne intermediates.



中文翻译:

吡啶并[1,2-a]吲哚的合成方法(微综述)

综述介绍了过去十年来合成吡啶并[1,2- a ]吲哚及其环状和共轭衍生物的主要方法。根据起始化合物的不同,该方法分为三类:在吲哚片段上构建吡啶核,使用苄基取代的吡啶进行环化以及通过芳烃中间体进行一步法成型。

更新日期:2020-10-30
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