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Synthetic approaches to pyrido[1,2-a]indoles (microreview)

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Chemistry of Heterocyclic Compounds Aims and scope

The review presents the main methods for the synthesis of pyrido[1,2-a]indoles and their annulated and conjugated derivatives over the past 10 years. The approaches are divided into three groups depending on the starting compounds: construction of the pyridine nucleus on the indole fragment, cyclization using benzylsubstituted pyridines, and formally one-step process via aryne intermediates.

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This work was supported by the Russian Science Foundation (grant 18-13-00365).

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Authors and Affiliations

  1. Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., K-2, Yekaterinburg, 620002, Russia

    Igor L. Nikonov, Dmitry S. Kopchuk, Grigory V. Zyryanov & Oleg N. Chupakhin

  2. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi / 20 Akademicheskaya St., Yekaterinburg, 620108, Russia

    Igor L. Nikonov, Dmitry S. Kopchuk, Grigory V. Zyryanov & Oleg N. Chupakhin

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  1. Igor L. Nikonov
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  2. Dmitry S. Kopchuk
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  3. Grigory V. Zyryanov
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  4. Oleg N. Chupakhin
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Correspondence to Dmitry S. Kopchuk.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(9), 1155–1157

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Nikonov, I.L., Kopchuk, D.S., Zyryanov, G.V. et al. Synthetic approaches to pyrido[1,2-a]indoles (microreview). Chem Heterocycl Comp 56, 1155–1157 (2020). https://doi.org/10.1007/s10593-020-02790-6

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  • DOI: https://doi.org/10.1007/s10593-020-02790-6

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