Abstract

Pyridazine and pyridazinone are heterocycles that contain two adjacent nitrogen atoms and shown wide range of pharmacological activities such as antimicrobial, antidepressant anti-hypertensive, anticancer, antiplatelet, antiulcer, herbicidal, antifeedant and various other anticipated biological activities. Pyridazine ring are present in some commercially available drugs and agrochemicals. Pyridazine based systems have been shown to have numerous practical applications.

中文翻译：

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具有生物活性的哒嗪和哒嗪酮衍生物：一种高度官能化化合物的支架

摘要

哒嗪和哒嗪酮是含有两个相邻氮原子的杂环，它们具有广泛的药理活性，例如抗微生物剂，抗抑郁药，抗高血压药，抗癌药，抗血小板药，抗溃疡药，除草剂，抗饲料药和各种其他预期的生物学活性。哒嗪环存在于一些市售药物和农用化学品中。基于哒嗪的系统已显示具有许多实际应用。