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Biologically Active Pyridazines and Pyridazinone Derivatives: A Scaffold for the Highly Functionalized Compounds

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Abstract

Pyridazine and pyridazinone are heterocycles that contain two adjacent nitrogen atoms and shown wide range of pharmacological activities such as antimicrobial, antidepressant anti-hypertensive, anticancer, antiplatelet, antiulcer, herbicidal, antifeedant and various other anticipated biological activities. Pyridazine ring are present in some commercially available drugs and agrochemicals. Pyridazine based systems have been shown to have numerous practical applications.

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  1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, 91911, PO Box 840, Rafha, Saudi Arabia

    Mohd Imran

  2. Department of Pharmacy, Himalayan Institute of Pharmacy and Research, 248007, Dehradun, (Uttarakhand), India

    Mohammad Asif

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Mohd Imran, Mohammad Asif Biologically Active Pyridazines and Pyridazinone Derivatives: A Scaffold for the Highly Functionalized Compounds. Russ J Bioorg Chem 46, 726–744 (2020). https://doi.org/10.1134/S1068162020050155

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