Much attention is given to research and development of efficient systems for the delivery of essential omega-3-polyunsaturated fatty acids and other nutraceuticals to the human body with food. Nanocomplexes, which are based on soybean phosphatidylcholine liposomes with nutraceuticals included, are among the efficient delivery systems. The prolonged use of these nanocomplexes may affect the antioxidant status in various organs and tissues. In this work, thermo-initiated chemiluminescence was used to study changes in the antioxidant activity of the blood plasma, liver, and brain lipids in mice divided into six groups depending on the composition of liposomal nanocomplexes introduced into drinks substituted for water in a long-term (3 month) diet. The components of six types of liposomal nanocomplexes, except for phosphatidylcholine, in different combinations were clove essential oil, fish oil, and sodium caseinate. The results of the study showed that nanocomplexes containing liposomes made of phosphatidylcholine with the addition of fish oil and clove essential oil and encapsulated in milk protein (sodium caseinate) proved to be the most effective in increasing the antioxidant activity of the blood plasma and brain lipids in mice compared to the control.

人们一直在研究和开发有效的系统，以通过食物将必需的omega-3-多不饱和脂肪酸和其他营养品输送到人体。基于大豆磷脂酰胆碱脂质体（包括营养品）的纳米复合物是有效的递送系统。长时间使用这些纳米复合物可能会影响各种器官和组织中的抗氧化剂状态。在这项工作中，使用热引发化学发光技术研究了小鼠血浆，肝脏和脑脂质的抗氧化活性的变化，这些脂质分为六组，具体取决于引入脂质饮料的纳米复合物的组成，该复合物在长期饮用的水中代替水。长期（3个月）饮食。除磷脂酰胆碱以外，六种脂质体纳米复合物的成分 丁香精油，鱼油和酪蛋白酸钠以不同的组合形式存在。研究结果表明，纳米复合物包含磷脂酰胆碱制成的脂质体，鱼油和丁香精油，并包裹在乳蛋白（酪蛋白酸钠）中，被证明是最有效的增加血浆和脑脂质的抗氧化活性的化合物。与对照组相比。