Ablation of pulmonary veins has emerged as a key procedure for normal rhythm restoration in atrial fibrillation patients. However, up to half of ablated Atrial fibrillation (AF) patients suffer recurrences during the first year. In this article, simultaneous intra-atrial recordings registered at pulmonary veins previous to the ablation procedure were analyzed. Spatial cross-correlation and transfer entropy were computed in order to estimate spatial organization. Results showed that, in patients with arrhythmia recurrence, pulmonary vein electrical activity was less correlated than in patients that maintained sinus rhythm. Moreover, correlation function between dipoles showed higher delays in patients with AF recurrence. Results with Transfer Entropy were consistent with spatial cross-correlation measurements. These results show that arrhythmia drivers located at the pulmonary veins are associated with a higher organization of the electrical activations after the ablation of these sites.

中文翻译：

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肺静脉活动组织，以确定房颤复发：一项初步研究的初步数据。

消融肺静脉已成为房颤患者恢复正常心律的关键方法。但是，消融的心房颤动（AF）患者中有多达一半在第一年复发。在本文中，分析了消融手术之前在肺静脉处同时记录的心房内记录。计算空间互相关和传递熵，以估计空间组织。结果表明，在有心律失常复发的患者中，与维持窦性心律的患者相比，肺静脉电活动的相关性较小。此外，偶发子之间的相关函数在房颤复发患者中显示出更高的延迟。传递熵的结果与空间互相关测量结果一致。