Transcranial direct current stimulation of the cerebellum (c-tDCS) improves motor performance in young and old adults. Based on the cerebellar involvement in Parkinson’s disease (PD), c-tDCS could have potential to improve motor function in PD. The purpose was to determine the effects of c-tDCS on motor performance in PD while participants were on medications. The study was a randomized, double-blind, SHAM-controlled, between-subjects design. Twenty-two participants with PD were allocated to either a c-tDCS group or a SHAM group. All participants completed one experimental session and performed two motor tasks with their most affected hand in a Baseline condition (no stimulation) and an Experimental condition. The motor tasks were a visuomotor isometric precision grip task (PGT) and a rapid arm movement task (AMT). The primary dependent variables were force error and endpoint error in the PGT and AMT, respectively. There were no significant differences in force error or endpoint error in the Experimental condition between the c-tDCS and SHAM groups. These results indicate that an acute application of c-tDCS does not enhance motor performance in hand and arm tasks in PD. Longer-term c-tDCS application over multiple days may be needed to enhance motor function in PD.

中文翻译：

---

小脑经颅直流电刺激的急性应用并不能改善帕金森氏病的运动表现

经颅直流小脑（c-tDCS）可以改善年轻人和老年人的运动能力。基于小脑参与帕金森氏病（PD），c-tDCS可能具有改善PD运动功能的潜力。目的是确定参与者服用药物时c-tDCS对PD运动功能的影响。该研究是一项随机，双盲，SHAM控制的受试者间设计。22名PD患者被分配到c-tDCS组或SHAM组。所有参与者都完成了一个实验会话，并在基准条件（无刺激）和实验条件下用受影响最大的手执行了两项运动任务。运动任务是粘性运动等距精确抓地力任务（PGT）和快速手臂运动任务（AMT）。主要因变量分别是PGT和AMT中的力误差和终点误差。在c-tDCS和SHAM组之间，在实验条件下，力误差或终点误差没有显着差异。这些结果表明，急性应用c-tDCS并不能增强PD中手部和手臂任务的运动能力。可能需要连续几天服用c-tDCS，以增强PD的运动功能。