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Biological and Chemical Assessment of Ochrosia elliptica Labill Leaves
Arabian Journal for Science and Engineering ( IF 2.6 ) Pub Date : 2020-10-12 , DOI: 10.1007/s13369-020-04986-6
Riham A. El-Shiekh , Dalia A. Al-Mahdy , Mohamed S. Hifnawy , Essam Abdel-Sattar

Ochrosia elliptica Labill is a small tropical evergreen tree native to Oceania belonging to the Apocynaceae family. Eight alkaloids, two flavonoid glycosides and three phenolic acids were identified by LC/MS analysis. On the other hand, the quality and uniformity of the plant leaves were assessed through the determination of the total phenolic and flavonoid, in addition to total ash, acid-insoluble ash, water-soluble ash and moisture content. The total ethanolic and aqueous extracts of the leaves of O. elliptica as well as their fractions were investigated for their antinociceptive (analgesic) using tail-flick test and antimicrobial activities using agar well diffusion assay. Among the tested fractions, the results showed that the n-butanol fraction exhibited high potency as antinociceptive compared to indomethacin drug and as antifungal compared to amphotericin B.



中文翻译:

椭圆ch草叶片的生化评估

Ochrosia elliptica Labill是一棵小热带常绿树,原产于大洋洲,属于夹竹桃科。通过LC / MS分析鉴定出八种生物碱,两种黄酮苷和三种酚酸。另一方面,除总灰分,酸不溶性灰分,水溶性灰分和水分含量外,还通过测定总酚和类黄酮来评估植物叶片的质量和均匀性。用甩尾法研究了椭圆形枫叶的总乙醇提取物和水提取物及其馏分的抗伤害性(镇痛作用),并使用琼脂井扩散试验研究了其抗菌活性。在供试的馏分,结果表明,Ñ与吲哚美辛药物相比,-丁醇级分具有较高的抗伤害感受性,与两性霉素B相比,具有较高的抗真菌作用。

更新日期:2020-10-12
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