Rapid on-site detection of glucose has been attracting considerable attention nowadays. Screen-printed electrodes (SPEs) were assessed as ideal detection platforms due to their advantages such as, disposability, portability, ease of miniaturization, and mass production. The topology and shape of electrodes have a crucial impact on their electrical conductivity and electrochemical properties. In this study, a versatile electrochemical platform with optimized three-electrode configuration was developed through screen-printing technology. Three types of SPEs were prepared, and their electrocatalytic properties toward glucose detection were investigated. Based on this platform, both enzyme-based (denoted as GOD/rGO) and non-enzymatic (denoted as Co@MoS₂/rGO) bioactive compounds were deposited on the working electrode of the circular SPE through simply drop-casting, respectively. Their morphology was characterized through scanning electron microscopy (SEM). Cycle sweep voltammetry was used to study the electrocatalytic activity of these biosensors. The circular SPE exhibited satisfying electrochemical redox activity and much higher sensitivity towards glucose detection, which rendered it a promising candidate for point-of-care detection.

如今，葡萄糖的快速现场检测已引起人们的广泛关注。丝网印刷电极（SPE）因其一次性、便携、易于小型化和大规模生产等优点而被认为是理想的检测平台。电极的拓扑和形状对其电导率和电化学性能具有至关重要的影响。在这项研究中，通过丝网印刷技术开发了具有优化三电极配置的多功能电化学平台。制备了三种类型的 SPE，并研究了它们对葡萄糖检测的电催化性能。基于该平台，通过简单的滴铸，将酶基（表示为GOD/rGO）和非酶基（表示为Co@MoS ₂ /rGO）生物活性化合物分别沉积在圆形SPE的工作电极上。它们的形态通过扫描电子显微镜（SEM）进行表征。使用循环扫描伏安法来研究这些生物传感器的电催化活性。圆形 SPE 表现出令人满意的电化学氧化还原活性和对葡萄糖检测更高的灵敏度，这使其成为即时检测的有希望的候选者。