This article presents a new perspective on the development of inorganic scintillator-based fiber dosimeters (IOSFDs) for medical radiotherapy dosimetry (RTD) focusing on real-time in vivo dosimetry. The scintillator-based optical fiber dosimeters (SFD) are compact, free of electromagnetic interference, radiation-resistant, and robust. They have shown great potential for real-time in vivo RTD. Compared with organic scintillators (OSs), inorganic scintillators (IOSs) have larger X-ray absorption and higher light output. Variable IOSs with maximum emission peaks in the red part of the spectrum offer convenient stem effect removal. This article outlines the main advantages and disadvantages of utilizing IOSs for SFD fabrication. IOSFDs with different configurations are presented, and their use for dosimetry in X-ray RT, brachytherapy (BT), proton therapy (PT), and boron neutron capture therapy (BNCT) is reviewed. Challenges including the percentage depth dose (PDD) deviation from the standard ion chamber (IC) measurement, the angular dependence, and the Cherenkov effect are discussed in detail; methods to overcome these problems are also presented.

中文翻译：

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无机闪烁体光纤剂量计研究进展

本文提出了用于医学放射治疗剂量测定 (RTD) 的基于无机闪烁体的光纤剂量计 (IOSFD) 开发的新视角，重点关注实时体内剂量测定。基于闪烁体的光纤剂量计 (SFD) 结构紧凑、无电磁干扰、抗辐射且坚固耐用。它们在实时体内 RTD 方面表现出了巨大的潜力。与有机闪烁体（OS）相比，无机闪烁体（IOS）具有更大的X射线吸收和更高的光输出。可变 IOS 的最大发射峰位于光谱的红色部分，可方便地消除茎效应。本文概述了利用 IOS 进行 SFD 制造的主要优点和缺点。介绍了具有不同配置的 IOSFD，并回顾了它们在 X 射线 RT、近距离放射治疗 (BT)、质子治疗 (PT) 和硼中子捕获治疗 (BNCT) 中剂量测定的应用。详细讨论了挑战，包括百分比深度剂量 (PDD) 与标准电离室 (IC) 测量的偏差、角度依赖性和切伦科夫效应；还提出了克服这些问题的方法。