In recent years, the frequency of infections due to saprophytic fungi has increased. Cryptococcus laurentii, recently classified as Papiliotrema laurentii, is responsible for fungemia, meningitis, and superficial infections. Here, we report the first case of cutaneous Papiliotrema (Cryptococcus) laurentii infection in a 23-year-old Caucasian woman affected by an autoimmune thyroiditis with hypothyroidism. Impairments of the immune system are often associated with unusual fungal infections, which cannot be neglected. The isolate strain was susceptible to Amphotericin B while resistant to fluconazole, itraconazole, voriconazole, and terbinafine. The patient was successfully treated with Amphotericin B.

近年来，由腐生真菌引起的感染频率有所增加。最近归类为Papiliotrema laurentii 的Cryptococcus laurentii是导致真菌血症、脑膜炎和浅表感染的原因。在这里，我们报告皮肤首例Papiliotrema（隐）罗伦在受甲状腺功能减退的自身免疫性甲状腺炎一名23岁的白人妇女感染。免疫系统的损伤通常与异常的真菌感染有关，这一点不容忽视。该分离株对两性霉素 B 敏感，同时对氟康唑、伊曲康唑、伏立康​​唑和特比萘芬耐药。患者用两性霉素 B 成功治疗。