Hydroxyapatite (HAp) has been widely used as an implant material for repairing or substituting human hard tissues due to its close similarity in composition to the natural bone and teeth. Many researchers are preparing HAp from natural and chemical sources. Generally, the products from the chemical sources are incompatible and do not meet out the biomedical demand. Thus, the present study is focused to compare the products from both natural and chemical sources through microwave irradiation method. For synthesizing HAp, calcium source was achieved from commercial calcium nitrate (Ca (NO₃)₂ 4H₂O) and sea shell (Murex virgineus) as CaO. The effect of polymers (poly ethylene glycol (PEG) and poly vinyl alcohol (PVA)) on both natural and chemically derived HAp is examined. For making better comparison, synthesized products have been characterized by Fourier transform infrared spectroscopy, x-ray diffraction analysis, scanning electron microscopy, transmission electron microscopy with SAED pattern, and antibacterial activity. Better rod-like morphology and suitable crystallinity are achieved in the naturally derived HAp. The overall results show that the polymer-assisted nanohydroxyapatite (nHAp) from Murex virgineus could enhance properties such as size, shape, surface area, and antibacterial activity.

羟基磷灰石（HAp）由于其成分与天然骨骼和牙齿非常相似，因此已被广泛用作修复或替代人类硬组织的植入材料。许多研究人员正在从天然和化学来源制备HAp。通常，化学来源的产品不相容，无法满足生物医学需求。因此，本研究致力于通过微波辐照方法比较天然和化学来源的产品。为了合成HAp，钙的来源来自商业硝酸钙（Ca（NO ₃）₂ 4H ₂ O）和贝壳（Murex virgineus）作为CaO。研究了聚合物（聚乙二醇（PEG）和聚乙烯醇（PVA））对天然和化学衍生HAp的影响。为了进行更好的比较，已通过傅里叶变换红外光谱，X射线衍射分析，扫描电子显微镜，具有SAED模式的透射电子显微镜和抗菌活性对合成产物进行了表征。天然来源的HAp具有更好的棒状形态和合适的结晶度。总体结果表明，来自Murex virgineus的聚合物辅助的纳米羟基磷灰石（nHAp）可以增强诸如尺寸，形状，表面积和抗菌活性等特性。