Maturity-onset diabetes of the young (MODY) represents a heterogenous group of monogenic autosomal dominant diseases, which accounts for 1–2% of all diabetes cases. Pregnancy represents a crucial time to diagnose MODY forms due to the 50% risk of inheritance in offspring of affected subjects and the potential implications on adequate fetal weight. Not only a history of maternal diabetes may affect the birth weight of offspring, paternal diabetes should also be taken into consideration for a correct pathogenetic diagnosis. The crucial role of maternal and paternal diabetes inheritance patterns and the impact of this inherited mutation on birthweight and the MODY diagnosis was discussed.

中文翻译：

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母体或父体糖尿病及其在后代出生体重和MODY诊断中的关键作用

年轻人的成熟期糖尿病（MODY）代表单基因常染色体显性遗传疾病的异质性组，占所有糖尿病病例的1-2％。怀孕是诊断MODY形式的关键时刻，因为受影响对象的后代有50％的遗传风险以及对胎儿体重的潜在影响。母体糖尿病史不仅可能影响后代的出生体重，还应考虑母体糖尿病以进行正确的病原学诊断。讨论了母体和父体糖尿病遗传模式的关键作用以及这种遗传突变对出生体重和MODY诊断的影响。