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Nucleophilic substitution of the nitro group in 1-substituted 3-nitro-1 H -1,2,4-triazoles in ethanolic potassium hydroxide
Chemistry of Heterocyclic Compounds ( IF 1.5 ) Pub Date : 2020-09-23 , DOI: 10.1007/s10593-020-02780-8
Ani H. Hasratyan , Astkhik А. Sukoyan , Aleksan G. Shakhatuni , Gevorg G. Danagulyan , Hovhannes S. Attaryan

Dehydrochlorination of 1-(2-chloroethyl)-3-nitro-1H-1,2,4-triazole in ethanolic potassium hydroxide is accompanied by nucleophilic substitution of the nitro group by the ethoxy group. The same nucleophilic exchange in 1-substituted 3-nitro-1H-1,2,4-triazoles occurs in methanol and n-propanol solutions of potassium hydroxide.



中文翻译:

乙醇氢氧化钾中1-取代的3-硝基-1 H -1,2,4-三唑中硝基的亲核取代

1-(2-氯乙基)-3-硝基-1 H -1,2,4-三唑在乙醇氢氧化钾中的脱氯化氢反应伴随着硝基被乙氧基的亲核取代。在1-取代的3-硝基-1 H -1,2,4-三唑中,相同的亲核交换发生在氢氧化钾的甲醇和正丙醇溶液中。

更新日期:2020-09-23
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