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Disconnecting surgery at alveus and cornu ammonis of hippocampus, amygdala superficialis, and amygdala medial nuclei for epilepsy associated with attention deficit hyperactivity disorder.
Child's Nervous System ( IF 1.3 ) Pub Date : 2020-09-19 , DOI: 10.1007/s00381-020-04893-z
Zamzuri Idris 1, 2, 3 , Zaitun Zakaria 1, 2, 3 , Sanihah Abdul Halim 3, 4 , Salmi Abd Razak 3, 5 , Abdul Rahman Izaini Ghani 1, 2, 3 , Jafri Malin Abdullah 1, 2, 3
Affiliation  

The neural basis for epilepsy and attention deficit hyperactivity disorder (ADHD) is currently incompletely known. We reported a young girl with both epilepsy and ADHD, who had a calcified lesion in the right basolateral amygdalo-hippocampal region extending to the ventral striatum. The child underwent disconnecting surgery and biopsy of the lesion. Fascinatingly, the child’s behavior changed immediately after the surgery from inattentive and impulsive to nearly normal behavior experiencing no more breakthrough seizures since after 3 years of surgery. The Schaltenbrand Wahren Brain Atlas revealed alveus, cornu ammonis, amygdala superficialis, and medium as the disconnected region in this surgery.



中文翻译:

在海马的牙槽骨和角部、浅表杏仁核和杏仁核内侧核处断开手术,用于治疗与注意力缺陷多动障碍相关的癫痫症。

癫痫和注意力缺陷多动障碍 (ADHD) 的神经基础目前尚不完全清楚。我们报告了一名患有癫痫和多动症的年轻女孩,她在右侧基底外侧杏仁核 - 海马区有一个钙化病变,延伸至腹侧纹状体。孩子接受了断路手术和病灶活检。令人着迷的是,手术后孩子的行为立即从漫不经心和冲动转变为近乎正常的行为,自手术 3 年后不再出现突破性癫痫发作。Schaltenbrand Wahren 脑图谱显示,牙槽骨、眼角、浅杏仁核和中层是这次手术中的断开区域。

更新日期:2020-09-20
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