Abstract

A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and sacrificial layers of nonmagnetic metal is proposed. A method for template-assisted synthesis based on ac-potential electroplating of specified metals in the pores of track membranes is used to fabricate wires with a diameter of 100 nm with nickel layers of 400 and 200 nm. A method for the subsequent extraction of nickel fragments using selective etching (removal) of copper fragments is developed. Procedures that prevent aggregation of magnetic nanoparticles and penetration of the nanoparticles in the shells of polymer capsules are considered.

中文翻译：

---

圆柱形磁性纳米粒子的制备功能的聚电解质微胶囊。

摘要

考虑了用于靶向药物递送的磁性聚合物胶囊的制造问题。磁性纳米粒子用于研究的问题。提出了一种用于制造这种颗粒的方法，该方法包括合成具有指定磁性金属和非磁性金属的牺牲层的交替层的层状纳米线。一种基于在轨迹膜的孔中对特定金属进行电位电镀的模板辅助合成方法，用于制造直径为100 nm，镍层为400和200 nm的导线。开发了一种使用铜碎片的选择性蚀刻（去除）来随后提取镍碎片的方法。考虑了防止磁性纳米颗粒聚集和纳米颗粒渗透到聚合物胶囊壳中的程序。