A new isocoumarin compound named setosphacohol A (1), together with six known ones, alternariol (2), isoaltenuene (3), phomasatin (4), alternariol 5-O-methyl ether (5), 1-deoxyrubralactone (6), and rubralactone (7), was isolated from the entomogenous fungus Setosphaeria sp. The structure of the new compound was elucidated by analysis of the 1D and 2D spectroscopic data as well as MS. Compounds 2, 5, 6 showed moderate cytotoxicity against six human tumor cell lines MCF-7, MGC-803, H1975, Huh-7, A549, and HeLa with IC₅₀ values ranging from 23.04 to 96.91 μg·mL^–1.

中文翻译：

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虫生真菌Setosphaeria sp。的香豆素的分离和细胞毒性。

一种新的异香豆素化合物，称为setosphacohol A（1），以及六个已知的异香豆素化合物，交替烯醇（2），异altenuene（3），phomasatin（4），交替素5-O-甲基醚（5），1-脱氧丁香内酯（6），从昆虫病原菌Setosphaeria sp。中分离到了七甲基异戊二烯和红内酯（7）。通过分析1D和2D光谱数据以及MS阐明了新化合物的结构。化合物2，5，6显示对6个人肿瘤细胞系MCF-7，MGC-803，H1975，的Huh-7，A549，和HeLa与IC温和的细胞毒性₅₀值范围从23.04到96.91μg·mL ^–1。