This review summarizes the main directions and recent trends in the synthesis of isoxazoles, and also provides examples of the use of isoxazoles as biologically active compounds in medicinal chemistry. When discussing the classical methods of isoxazole synthesis, the main emphasis is placed on the problem of selectivity of transformations. Bibliography includes 112 sources.

中文翻译：

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异恶唑合成和使用的主要方向和最新趋势

这篇综述总结了异恶唑合成的主要方向和最新趋势，并提供了将异恶唑用作药物化学中生物活性化合物的实例。当讨论异恶唑合成的经典方法时，主要重点放在转化的选择性问题上。参考书目包括112个来源。