Abstract

A global analysis of the fluorescence decay kinetics of a chloroform extract of lipofuscin granules from the retinal pigment epithelium cells of human cadaver eyes is performed. The analysis makes it possible to reconstruct the individual fluorescence properties of four groups of fluorophores belonging to bisretinoids and the products of their photooxidation and photodegradation. The characteristic fluorescence lifetimes are correlated with the spectral characteristics of the indicated fluorophore groups using the averaged spectral and kinetic characteristics of the chloroform extract.

中文翻译：

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从人眼的视网膜色素上皮细胞重建类视黄醇的荧光光谱及其光氧化和光降解产物

摘要

进行了从人尸眼的视网膜色素上皮细胞中的脂褐素颗粒的氯仿提取物的​​荧光衰减动力学的全局分析。该分析使得有可能重建属于类视黄醇的四组荧光团的单个荧光性质以及它们的光氧化和光降解产物。使用氯仿提取物的​​平均光谱和动力学特征，特征荧光寿命与所示荧光团的光谱特征相关。