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A Convenient One-Pot Synthesis of 1,5-Disubstituted Tetrazoles Containing an Amino or a Carboxy Group
Russian Journal of Organic Chemistry ( IF 0.8 ) Pub Date : 2020-06-26 , DOI: 10.1134/s1070428020050127 N. T. Pokhodylo , O. Ya. Shyyka , M. D. Obushak
中文翻译:
方便的一锅合成含有氨基或羧基的1,5-二取代的四唑
更新日期:2020-06-26
Russian Journal of Organic Chemistry ( IF 0.8 ) Pub Date : 2020-06-26 , DOI: 10.1134/s1070428020050127 N. T. Pokhodylo , O. Ya. Shyyka , M. D. Obushak
Abstract
A convenient method is proposed for constructing the tetrazole ring by a one-pot reaction of amides with phosphorus oxychloride and sodium azide. A series of 1,5-disubstituted tetrazoles containing an amino or a carboxy group, which present interest as buildings blocks for the synthesis of biologically active substances, were obtained.中文翻译:
方便的一锅合成含有氨基或羧基的1,5-二取代的四唑