The properties of gold nanoparticles, such as conductivity, half-life, catalytic nature, improved solubility efficiency, chemical stability, and its mechanism in binding with bacterial cell wall to induce cell death, have increased its medicinal applications. This study investigated the antibacterial property of gold nanoparticles (AuNPs) synthesized from Garcinia kola pulp extract. The ripe fruits of Garcinia kola were obtained, and the pulps were removed, air dried, pulverized, extracted, and mixed with gold chloride solution following standard procedure. The synthesized AuNPs were characterized using ultraviolet visible spectrophotometer (UV-visible), Fourier transform infrared (FTIR) spectrophotometer, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy-dispersive X-ray (EDX). The antibacterial examination was carried out on four clinical isolate bacteria using agar diffusion technique. The UV-visible analysis confirmed the formation of stable AuNPs at pH 7 in the wavelength region of 564 nm. The FTIR analysis confirmed that the secondary metabolites with –OH functional groups serve as the reducing agent for the synthesis of AuNPs. The morphological assessment of the synthesized AuNPs revealed spherical-shaped particles. The zones of inhibition of the synthesized AuNPs against test bacteria ranges from 3 to 13 mm while that of the control was in the range of 14 to 22 mm. This study provided an environmentally friendly approach in the synthesis of AuNPs from Garcinia kola pulps and also ascertained the medicinal application of the synthesized AuNPs as an antibacterial agent.

金纳米颗粒的性质，例如电导率，半衰期，催化性质，改善的溶解效率，化学稳定性以及其与细菌细胞壁结合以诱导细胞死亡的机制，增加了其医学应用。这项研究调查了从藤黄果浆提取物合成的金纳米颗粒（AuNPs）的抗菌性能。藤黄的成熟果实获得所得的果肉，并按照标准程序将果肉除去，风干，粉碎，提取并与氯化金溶液混合。使用紫外可见分光光度计（UV-visible），傅立叶变换红外（FTIR）分光光度计，扫描电子显微镜（SEM），透射电子显微镜（TEM）和能量色散X射线（EDX）对合成的AuNP进行表征。使用琼脂扩散技术对四种临床分离菌进行了抗菌检查。紫外可见分析证实在pH 7处在564 nm波长范围内形成稳定的AuNP。FTIR分析证实具有-OH官能团的次生代谢产物可作为AuNPs合成的还原剂。合成的AuNPs的形态学评估显示球形颗粒。合成的AuNP对测试细菌的抑制区域为3至13mm，而对照的抑制区域为14至22mm。这项研究提供了一种环境友好的方法，可从中合成AuNP藤黄果浆，还确定了合成的AuNPs作为抗菌剂的医学应用。