In this paper, we discuss experimental data obtained during study of the effect of a low-frequency alternating magnetic field on the conformational transitions of human serum albumin in the presence of silver nanoparticles using fluorescence spectroscopy at different pH values. A sharp increase in the albumin fluorescence intensity was detected in the presence of silver nanoparticles; this effect changed when exposed to a low-frequency alternating magnetic field. The resulting calculation formula for cross section of light scattering by a spherical nanoparticle of a certain radius allows calculation of the sizes of nano-microstructures based on nanoparticles and natural biopolymers of the “core–shell” type, whose physicochemical properties can be controlled by a magnetic field. The proposed model for the formation of protein–nanoparticle associates in the solution by the dipole–dipole mechanism is in good agreement with the experimental data.

中文翻译：

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交变磁场和银纳米颗粒对人血清白蛋白水溶液光谱特征的影响

在本文中，我们讨论了在不同 pH 值下使用荧光光谱法研究低频交变磁场对银纳米颗粒存在下人血清白蛋白构象转变的影响期间获得的实验数据。在银纳米粒子存在的情况下，检测到白蛋白荧光强度急剧增加；当暴露在低频交变磁场中时，这种效果发生了变化。由一定半径的球形纳米颗粒产生的光散射截面的计算公式允许计算基于纳米颗粒和“核-壳”型天然生物聚合物的纳米微结构的尺寸，其物理化学性质可以通过磁场。