Abstract

In the estimation of immunobiochemical indices and the use of formalized statistics, clinical models of ischemic and hemorrhagic strokes aggravated by metabolic syndrome and of diffuse liver diseases have demonstrated the formation (under the influence of metabolic syndrome) of a reaction that is qualitatively homogeneous and quantitatively more pronounced with hemorrhagic stroke in the form of an imbalance in the primary and secondary products of free radical oxidation of lipids and proteins; the preferential activation of enzymatic and nonenzymatic mechanisms of the antioxidant system against a background of an accumulation of proinflammatory cytokines, and, in patients with diffuse liver diseases, the presence of a universal mechanism of the association of the intensity of oxidative stress (free radical oxidation) with the development of cytolytic syndrome, disorders of lipid metabolism, immune status, and the initiation of apoptosis mechanisms.

中文翻译：

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复杂成因疾病中的免疫代谢关联

摘要

在估计免疫生物化学指标和使用正式的统计数据时，由代谢综合征和弥漫性肝病加重的缺血性和出血性中风的临床模型已证明（在代谢综合征的影响下）定性和定量地反应的形成出血性中风更为明显，其形式是脂质和蛋白质的自由基氧化的一级和二级产物不平衡；在促炎性细胞因子积聚的背景下，抗氧化剂系统的酶促和非酶促机制被优先激活，并且在患有弥漫性肝病的患者中，